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首页> 外文期刊>Infectious disorders drug targets >Utility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise Bentham Science
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Utility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise Bentham Science

机译：Utility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise Bentham Science

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Purpose: Healthcare spending as a percentage of Gross domestic product (GDP) is atall-time high and continues to rise in the United States. The Centers for Medicare and MedicaidServices estimate that 33% of resources spent on healthcare goes to waste. As part of a ‘high valuecare’ exercise, we studied if estimating CD4 cell counts and HIV viral load in hospitalized patientswith a known diagnosis of HIV led to any meaningful change in HAART regimen and dischargediagnosis.Methods: Retrospective chart review for all patients admitted with a known diagnosis of HIVfrom January 1, through December 31, 2017.Results: A total of 83 patient encounters were reviewed during the period. The mean age was 54.1± 16.4 years, 64.1 % of patients were males. 75 patients (90.3%) were already on highly activeantiretroviral therapy (HAART). The median hospital length of stay (LOS) was 3 days (IQR 2.0 -5.0). The mean turnaround time for CD4 counts and HIV viral load assay was 2.9 days (95% CI2.1 – 3.7) and 3.9 days (95% CI, 3.2 – 4.6), respectively. A CD4 count estimation led to nochange in HAART regimen. HIV viral load assay testing had no impact on a change in treatmentor a change in diagnosis.Conclusions: In our study, testing CD4 counts and HIV viral load for inpatients did not conferany benefit in altering the diagnosis or HAART regimen. We believe that our study identifies asystems level opportunity to add to the concept of ‘Choosing Wisely.’.

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