Optimizing the allocation of higher education resources and improving the utilization efficiency of educational resources are of great significance to further promoting the balanced development of higher education quality. In order to rationalize and maximize the efficiency of the allocation of innovation and entrepreneurship education resources in colleges and universities and build an evaluation index system for the input and output of educational resources, this paper proposes to use the improved cytogenetic algorithm educational resources for resource allocation and utilization. The adaptive constraint processing technology is combined with the cytogenetic algorithm to avoid the algorithm falling into local optimum. Our method has achieved good results on high-dimensional functions. The utilization efficiency and allocation efficiency of innovation and entrepreneurship education resources in colleges and universities have increased by 21.33% and 18.92%, respectively, and tend to be in a balanced state, which can optimize the allocation of educational resources.
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