• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Muscle and Nerve >Which combined nerve conduction study scores are best suited for polyneuropathy in diabetic patients?
【24h】

Which combined nerve conduction study scores are best suited for polyneuropathy in diabetic patients?

机译：Which combined nerve conduction study scores are best suited for polyneuropathy in diabetic patients?

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

Abstract Introduction/Aims Nerve conduction studies (NCS) are widely used in diagnosing diabetic polyneuropathy. Combining the Z scores of several measures (Z‐compounds) may improve diagnostics by grading abnormality. We aimed to determine which combination of nerves and measures is best suited for studies of diabetic polyneuropathy. Methods Sixty‐eight patients with type 1 diabetes and 35 controls were included in this study. NCS measurements were taken from commonly investigated nerves in one arm and both legs. Different Z‐compounds were calculated and compared with reference material to assess abnormality. A sensitivity proxy, the accuracy index (AI), and Cohen's d were calculated. Results Z‐compounds with the highest AI consisted of the tibial and peroneal motor, and the sural, superficial peroneal, and tibial medial plantar sensory nerves in one or two legs. All Z‐compounds were able to discriminate between diabetic subjects and nondiabetic controls (mean Cohen's d?=?1.42 [range, 1.03‐1.63]). The association between AI and number of measures was best explained logarithmically (R2?=?0.401), with diminishing returns above approximately 14 or 15 measures. F‐wave inclusion may increase the AI of the Z compounds. Although often clinically useful among the non‐elderly, the additional inclusion of medial plantar NCS into Z‐compounds in general did not improve AI. Discussion Performing unilateral NCS in several motor and sensory lower extremity nerves is suited for the evaluation of polyneuropathy in diabetic patients. The use of Z‐compounds may improve diagnostic accuracy in diabetic polyneuropathy and may be particularly useful for follow‐up research studies as single summary measures of NCS abnormality development over time.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号