Novel Strategies and Model Studies for Colon Targeted Drug Delivery

Muath Sheet Mohammed Ameen; Rishabha Malviya; Omji PorwalEsra Tariq AnwarSumed-ha PantAkanksha Sharma

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Novel Strategies and Model Studies for Colon Targeted Drug Delivery

机译：Novel Strategies and Model Studies for Colon Targeted Drug Delivery

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Targeting drugs with controlled release characteristics to the colon is gaining importance for localized action as well as to improve the systemic availability of peptides and proteins. The present manuscript aims to describe the various approaches and model studies for colon targeted drug delivery. Drugs that have low absorption windows are targeted to the colonic regions using different novel technologies such as microparticulate systems, prodrugs, pH and time-dependent polymeric, effervescent and non-effervescent systems, etc. Along with this, this manuscript also describes the model study for colon targeting. Colon targeted drug delivery system offers the potential therapeutic benefits to patients in terms of both local and systemic treatment. These drugs can be directly targeted to the colon, which helps in reducing the systemic side effects.

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《Drug delivery letters》 |2021年第2期|156-163|共8页
作者
Muath Sheet Mohammed Ameen; Rishabha Malviya; Omji PorwalEsra Tariq AnwarSumed-ha PantAkanksha Sharma;
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作者单位

Department of Pharmacy, Tishk International University, Erbil-Kurdistan, Iraq;

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原文格式 PDF
正文语种英语
中图分类药学;
关键词
colon targeting; drug targeting; drug delivery; model study; colon; microparticulate systems.iii10.2174/2210303111666210118141406;

Novel Strategies and Model Studies for Colon Targeted Drug Delivery

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