Eastern Equine Encephalitis Virus Taxonomy, Genomics, and Evolution

Ciota Alexander T.

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Eastern Equine Encephalitis Virus Taxonomy, Genomics, and Evolution

机译：Eastern Equine Encephalitis Virus Taxonomy, Genomics, and Evolution

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Eastern equine encephalitis virus (EEEV; Togaviridae, Alphavirus) is an arthropod-borne virus (arbovirus) primarily maintained in an enzootic cycle between Culiseta melanura (Coquillett) and passerine birds. EEEV, which has the highest reported case- fatality rate among arbovirus in the Americas, is responsible for sporadic outbreaks in the Eastern and Midwest United States. Infection is associated with severe neurologic disease and mortality in horses, humans, and other vertebrate hosts. Here, we review what is known about EEEV taxonomy, functional genomics, and evolution, and identify gaps in knowledge regarding the role of EEEV genetic diversity in transmission and disease.

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《Journal of Medical Entomology》 |2022年第1期|14-19|共6页
作者
Ciota Alexander T.;
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作者单位

New York State Dept Hlth;

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原文格式 PDF
正文语种英语
中图分类基础医学;
关键词
NEUROINVASIVE ARBOVIRAL DISEASE; HEPARAN-SULFATE BINDING; SINDBIS VIRUS; ENCEPHALOMYELITIS VIRUS; UNITED-STATES; 6K PROTEIN; MOLECULAR EVOLUTION; CYTOPLASMIC DOMAIN; ANTIGENIC COMPLEX; CAPSID PROTEIN;

Eastern Equine Encephalitis Virus Taxonomy, Genomics, and Evolution

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