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Evaluation of the Status of Salivary Antioxidants in Dental Caries Bentham Science

机译：Evaluation of the Status of Salivary Antioxidants in Dental Caries Bentham Science

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Background and Aim: Dental caries is a communicable and the most prevalent infectiousdisease worldwide. Salivary oxidative stress and antioxidants may play a pivotal rolein caries prevention, progression and pathogenesis. In this study, salivary superoxide dismutase,peroxidase, glutathione peroxidase, catalase and uric acid levels were evaluated in dental caries.Materials and Methods: One hundred male and female students in two groups (n=50) were subdividedinto caries-active and caries-free (25) groups. Whole saliva samples were collected in themorning, and the salivary antioxidant levels were measured by a spectrophotometric assay. Thedata were analyzed using SPSS.Results: The caries-active group had higher peroxidase, uric acid, catalase and glutathione peroxidaselevels, and lower superoxide dismutase level as compared to the caries-free group. The comparisonbetween males and females showed lower peroxidase, catalase and uric acid levels andhigher glutathione peroxidase levels in the female group.Conclusion: The caries-active group had altered salivary antioxidant levels. Therefore, it wasconcluded that salivary antioxidants have significant effects on oral and dental health.

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