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机译:Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer
Ionis Pharmaceut;
AstraZeneca;
AstraZenecaAstraZeneca;
Immunity; Cellular; Immunotherapy; Therapies; Investigational; Tumor Microenvironment; Lymphocytes; Tumor-Infiltrating; REGULATORY T-CELLS; ANTI-CTLA-4 ANTIBODIES; EXPRESSION; INDUCTION; BLOCKADE; ACTIVATION; MECHANISMS; RESISTANCE; MUTATIONS; TOXICITY;