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Functional Encapsulating Structure for Wireless and Immediate Monitoring of the Fluid Penetration

机译:Functional Encapsulating Structure for Wireless and Immediate Monitoring of the Fluid Penetration

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摘要

With the fast-paced development of biomedical electronics, monitoring physiologicalprocesses have become ubiquitous throughout the field of implantabledevices. Nevertheless, inherent challenges remain extant when long-term applicationsare concerned. For the stable and reliable function of these devices,hermetic and biocompatible encapsulation is of paramount importance;however, extrinsic defects and intrinsic swelling properties of the encapsulatinglayer present the key limitation to ideal barrier performance. Thus, the abilityto monitor biofluid penetration and predict the device’s functional lifespan isnecessary for safe and stable operation within the body. This paper presentsthe functional encapsulation structure that quantitatively measures the diffusionof fluids into the encapsulation layer. The hydrolysis of Magnesium(Mg) electrodes underneath the encapsulating material shows the capabilityto wirelessly monitor the water penetration rate and the presence of defects,such as pinholes and cracks, in the encapsulating material. The experimentsconducted throughout this paper analyze the Mg thickness and geometry ofthe antenna to optimize the device’s susceptivity to water penetration whensubmerged in aqueous environments. The facile fabrication process and thecompatibility with prevailing implantable electronics further substantiate thedevice’s usability in diverse applications where chronic implants are necessaryfor monitoring disease or administering required treatments.

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