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Cognitive function, quality of life, and aging: relationships in individuals with and without spinal cord injury

机译:Cognitive function, quality of life, and aging: relationships in individuals with and without spinal cord injury

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Background: Correlations between aging, cognitive impairment and poor quality of life (QOL) have been observed for many patient populations. Objective: The purpose of this study was to examine these correlations in individuals with and without spinal cord injury (SCI). Methods: 23 individuals with complete SCI and 20 individuals without SCI ("NON") underwent assessment of cognitive function via the NIH Toolbox for Neurological and Behavioral Function. Participants self-rated QOL via global and symptom/domain-specific measures. Results: SCI rated global QOL to be lower than NON for the EQ-5D QALY (p 0.532) were absent in SCI. Significant correlations between cognition and QOL were prevalent for NON but not for SCI. Conclusions: Dissociation of age, cognition and QOL occurred with SCI. Divergence between EQ-5D QALY and VAS suggests that individuals with SCI may recalibrate personal assessments of QOL in ways that minimize the importance of mobility impairment.

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