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Asymmetric 'Janus' Biogel for Human-Machine Interfaces

机译:Asymmetric 'Janus' Biogel for Human-Machine Interfaces

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摘要

Human-machine interfaces (HMIs) are essential for effective communicationbetween machines and tissues. However, mechanical and biologicalmismatches, along with weak adhesion between rigid electronic devices andsoft tissue, often cause unreliable responses and affect the signal recording ofHMIs. In this study, an asymmetrical “Janus” biogel patch with one side firmlyadhering to tissues, and the other surface having little adhesion and minimalinteractions with surrounding environments has been developed. A series ofanalytical, mechanical, and electrical tests are performed to investigate the“Janus” biogel patch as a functional and biocompatible HMI. It is found thatthe gallic acid-modified gelatin adhesive surface on one side exhibits bodytemperature-dependent tissue adhesion, enabling low modulus and seamlessskin contact. The other side is a tough gelatin/glycerol gel layer, which isthermally welded into the adhesive layer and functions as an encapsulant toprevent external interference due to adhesion. The encapsulation layer alsoexhibits a low friction coefficient when wet and proves to be a reliablealternative barrier to conventional encapsulation materials. The scientificinsights and engineering principles revealed in this type of “Janus” biogel willbe applicable to a broad range of biomedical applications, such as epidermaladhesive electrodes or skin-adhesive wearable devices.

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