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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Simple Strategy Preparing Cyclodextrin Carboxylate as a Highly Effective Carrier for Bioactive Compounds
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Simple Strategy Preparing Cyclodextrin Carboxylate as a Highly Effective Carrier for Bioactive Compounds

机译：Simple Strategy Preparing Cyclodextrin Carboxylate as a Highly Effective Carrier for Bioactive Compounds

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摘要

Many phytochemicals suffer from poor water dispersity and storage stability, which restrict their application within aqueous-based commercial products. beta-Cyclodextrin (beta-CD) is a water-dispersible molecule with a hydrophobic core that can encapsulate and protect non-polar substances. The functional attributes of beta-CD can be further enhanced by chemical modification. In this study, a simple and effective dry-heating process was applied to fabricate succinic acid (SA)-modified beta-CD (SACD) through esterification. SACD showed better encapsulation property than non-modified beta-CD to guest molecules such as methyl orange (up to 1.41-folds of beta-CD) and curcumin (with an encapsulation efficiency of up to 10 mg/g). Meanwhile, higher water solubility (up to 469.30 g per 100 g of H2O) was achieved for SACD, indicating that a high dose of SACD could be applied in an aqueous food matrix. Such a simple strategy exhibiting low cytotoxicity shows great potential incorporating bioactive compounds into functional foods.

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