An Overview of Marketed Nucleoside and Nucleotide Analogs

Steven De Jonghe; Piet Herdewijn

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An Overview of Marketed Nucleoside and Nucleotide Analogs

机译：An Overview of Marketed Nucleoside and Nucleotide Analogs

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Nucleos(t)ide chemistry has been the subject of intense research, mainly because of the promising antiviral and antitumoral activity associated with this compound class. Numerous analogs have been synthesized over the past decades, yielding a number of derivatives that have reached the status of marketed drugs. Herein, an overview of the nucleos(t)ide analogs that have received marketing approval is given. The review is divided into several sections, including antiviral and antitumoral nucleoside analogs as well as nucleoside analogs that have received marketing approval in other therapeutic areas.

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《Current Protocols in Nucleic Acid Chemistry》 |2022年第3期|e376-1-e376-13|共13页
作者
Steven De Jonghe; Piet Herdewijn;
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作者单位

KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium;

KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Rega Institute for Medical Research, Laboratory of Medicinal Chemistry, Leuven, Belgium;

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原文格式 PDF
正文语种英语
中图分类生物化学;
关键词
antitumoral; antiviral; COVID-19; nucleoside; nucleotide;

An Overview of Marketed Nucleoside and Nucleotide Analogs

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