AbstractThe mode and the kinetics of the death of T‐thymoma cells upon dexamethasone treatment and γ‐irradiation (10Gy) have been studied using flow cytometry and biochemical analysis. It has been shown that the hormone and γ‐irradiation induce cell death by apoptosis. In both cases the cells are initially blocked in G2/M and die only after overcoming the blockage and cytokinesis. A short exposure to dexamethasone results in a cytostatic effect, whereas a cytotoxic effect is absent. Reducing serum concentration to 2% causes more rapid death both following γ‐irradiation and dexamethasone. These results are discussed in relation to cell death and pro
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