...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental Science & Technology: ES&T >Dietary Intake Contributed the Most to Chlorinated Paraffin Body Burden in a Norwegian Cohort
【24h】

Dietary Intake Contributed the Most to Chlorinated Paraffin Body Burden in a Norwegian Cohort

机译：Dietary Intake Contributed the Most to Chlorinated Paraffin Body Burden in a Norwegian Cohort

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

Determining the major human exposure pathways is a prerequisite for the development of effective management strategies for environmental pollutants such as chlorinated paraffins(CPs).As a first step,the internal and external exposure to CPs were quantified for a well-defined human cohort.CPs in participants'plasma and diet samples were analyzed in the present study,and previous results on paired air,dust,and hand wipe samples were used for the total exposure assessment.Both one compartment pharmacokinetic modeling and forensic fingerprinting indicate that dietary intake contributed the most to body burden of CPs in this cohort,contributing a median of 60-88% of the total daily intakes.The contribution from dust ingestion and dermal exposure was greater for the intake of long-chain CPs(LCCPs)than short-chain CPs@CCPs),while the contribution from inhalation was greater for the intake of SCCPs than medium-chain CPs(MCCPs)and LCCPs.Significantly higher concentrations of SCCPs and MCCPs were observed in diets containing butter and eggs,respectively(p < 0.05).Additionally,other exposure sources were correlated to plasma levels of CPs,including residence construction parameters such as the construction year(p < 0.05).This human exposure to CPs is not a local case.From a global perspective,there are major knowledge gaps in biomonitoring and exposure data for CPs from regions other than China and European countries.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号