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首页> 外文期刊>American pharmaceutical review >Process Analytical Technology and Digital Biomanufacturing of Monoclonal Antibodies
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Process Analytical Technology and Digital Biomanufacturing of Monoclonal Antibodies

机译：Process Analytical Technology and Digital Biomanufacturing of Monoclonal Antibodies

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摘要

Biomanufacturing is moving toward digital manufacturing with increased application of Process Analytical Technology (PAT) and continuous manufacturing. This article discusses strategies and components of the digital biomanufacturing approach, including mechanistic models and their validation, automation of the construction of models by data analytics and machine learning to improve efficiency and improve model quality, and real-time feedback control of critical quality attributes (CQAs).

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