Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies

Jocelyn Chan; Yue Wu; James WoodMohammad MuhitMohammed K. MahmoodTasneem KarimFarhana MoushumiCheryl A. JonesTom SnellingGulam Khandaker

首页> 外文期刊>Infectious disorders drug targets >Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies

【24h】

Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies

机译：Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Background and Objectives: Congenital Rubella Syndrome (CRS) is the leading causeof vaccine-preventable congenital anomalies. Comprehensive country-level data on the burden ofCRS in low and middle-income countries, such as Bangladesh, are scarce. This information is essentialfor assessing the impact of rubella vaccination programs. We aim to systematically reviewthe literature on the epidemiology of CRS and estimate the burden of CRS in Bangladesh.Methods: We conducted a systematic review of existing literature and transmission modelling ofseroprevalence studies to estimate the pre-vaccine period burden of CRS in Bangladesh. OVIDMedline (1948 – 23 November 2016) and OVID EMBASE (1974 – 23 November 2016) weresearched using a combination of the database-specific controlled vocabulary and free text terms.We used an age-stratified deterministic model to estimate the pre-vaccination burden of CRS inBangladesh.Findings: Ten articles were identified, published between 2000 and 2014, including seven crosssectionalstudies, two case series and one analytical case-control study. Rubella seropositivityranged from 47.0% to 86.0% among all age population. Rubella sero–positivity increased withage. Rubella seropositivity among women of childbearing age was 81.0% overall. The estimatedincidence of CRS was 0·99 per 1,000 live births, which corresponds to approximately 3,292 CRScases annually in Bangladesh.Conclusion: The estimated burden of CRS in Bangladesh during the pre-vaccination period washigh. This will provide important baseline information to assess the impact and cost-effectivenessof routine rubella immunisation, introduced in 2012 in Bangladesh.

著录项

来源
《Infectious disorders drug targets》 |2020年第3期|284-290|共7页
作者
Jocelyn Chan; Yue Wu; James WoodMohammad MuhitMohammed K. MahmoodTasneem KarimFarhana MoushumiCheryl A. JonesTom SnellingGulam Khandaker;
展开▼
作者单位

Murdoch Childrens Research Institute, Royal Children’s Hospital;

Curtin University, School of Public Health;

School of Public Health and Community Medicine, University of New South WalesCSF GlobalCentral Queensland Hospital and Health Services;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类药学;
关键词
Rubella; Congenital rubella syndrome; CRS; Transmission modelling; Bangladesh;

Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies

摘要

著录项

相关主题

期刊订阅