Electrically Evoked Compound Action Potential Studies Based on Finite Element and Neuron Models

Charles T. M. Choi; Dong Lin Wu

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Electrically Evoked Compound Action Potential Studies Based on Finite Element and Neuron Models

机译：Electrically Evoked Compound Action Potential Studies Based on Finite Element and Neuron Models

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Electrically evoked compound action potential (ECAP) represents a synchronous response of a group of nerve fibers activated by electrical stimulation. ECAP has been an important physiological signal for the cochlear implant (CI) used in various clinical studies. A 3-D CI model based on a patient’s medical images was created to simulate ECAP using the finite element method (FEM) and neuron models in this study. ECAPs obtained by alternating polarity approach were recorded by several sensing electrodes with different current levels. The least-square optimization method was used to calibrate the ECAP simulation results and they were compared with a patient’s clinical ECAP measurements. Results showed that calibrated simulations of ECAPs were consistent with the ECAP measurements. This study demonstrated that simulated ECAP based on CI models could be used as a reference for patient-specific CI studies for CI objective programming.

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《IEEE Transactions on Magnetics》 |2022年第1期|7501404-1-7501404-4|共4页
作者
Charles T. M. Choi; Dong Lin Wu;
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作者单位

National Yang Ming Chiao Tung University;

Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Yang Ming Chiao Tung University;

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正文语种英语
中图分类电工技术;
关键词
Cochlear implants (CIs); electromagnetic modeling; electrophysiology; finite element analysis; neuron models; Electrodes; Cochlear implants; Current measurement; Trajectory; Mathematical models; Finite element analysis; Computational modeling;

Electrically Evoked Compound Action Potential Studies Based on Finite Element and Neuron Models

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