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Synthesis,Spectral Characterization of Some Novel Schiff s base and its Antibacterial Studies

机译:Synthesis,Spectral Characterization of Some Novel Schiff s base and its Antibacterial Studies

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摘要

(E)-4,6-dibromo-N~1-(4-substituted benzylidene)benzene-1,2-diamine(1-6)(aryl = C6H5,p-FC6H4,p-ClC6H4,p-BrC6H4,p-CH3C6H4,p-CH3OC6H4)were synthesized by the condensation of 2-amino-4,6-dibromobenzaldehyde and 4-substituted aniline.Schiff bases.All compounds were evaluated for their in vitro antibacterial activity against different strains of Staphylococcus aureus,Bacillus subtilis,Streptococcus pyogenes,Klebsiella pneumoniae,E.coli and Pseudomonas aeruginosa with Chloramphenicol as standard drug.Out of all Schiff s basses,the compound 6 shows good activity against Klebsiella pneumoniae strains.

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