Biodegradable Polymer with Effective Near-Infrared-Ⅱ　Absorption as a Photothermal Agent for Deep Tumor　Therapy

Yu Yingjie; Tang Dongsheng; Liu ChaoyongZhang QiTang LinLu YunfengXiao Haihua

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Biodegradable Polymer with Effective Near-Infrared-Ⅱ　Absorption as a Photothermal Agent for Deep Tumor　Therapy

机译：Biodegradable Polymer with Effective Near-Infrared-Ⅱ　Absorption as a Photothermal Agent for Deep Tumor　Therapy

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Photothermal therapy holds great promise for cancer treatment due to its effective tumor ablation and minimal invasiveness. Herein a new class of biodegradable photothermal agents with effective adsorption in both near-infrared-I (NIR-I) and NIR-II windows is reported for deep tumor therapy. As demonstrated in a deep-seated ovarian cancer model, photothermal therapy using 1064 nm irradiation effectively inhibits tumor progression and prolongs survival spans. This work provides a new design of photothermal agents toward a more effective therapy of tumors.

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来源
《Advanced Materials》 |2022年第4期|2105976.1-2105976.8|共8页
作者
Yu Yingjie; Tang Dongsheng; Liu ChaoyongZhang QiTang LinLu YunfengXiao Haihua;
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Beijing Univ Chem Technol, State Key Lab Organ Inorgan Composites, Beijing Lab Biomed Mat, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, Beijing 100029, Peoples R China;

Beijing Univ Chem Technol, State Key Lab Organ Inorgan Composites, Beijing Lab Biomed Mat, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, Beijing 100029, Peoples R China|Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, State Key Lab Polymer Phys &;

Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USAUniv Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USAChinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China|Univ Chinese Acad Sci, Beijing 100049, Peoples R China;

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正文语种英语
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biodegradability; NIR-II window; ovarian cancer model; photothermal agents; photothermal therapy;

Biodegradable Polymer with Effective Near-Infrared-Ⅱ Absorption as a Photothermal Agent for Deep Tumor Therapy

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Biodegradable Polymer with Effective Near-Infrared-Ⅱ　Absorption as a Photothermal Agent for Deep Tumor　Therapy