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Contact sensitization to iron: A potentially underestimated metal allergen and elicitor of complications in patients with metal implants

机译：Contact sensitization to iron: A potentially underestimated metal allergen and elicitor of complications in patients with metal implants

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Abstract Background Little is known about sensitization to iron (Fe) in private, occupational, and medical settings, particulary implantology. Objectives To investigate sensitization to metals, particularly to Fe, both in pre‐implant individuals with presumed metal allergy and in patients with suspected metal implant allergy. To further characterize Fe‐sensitized individuals. Methods Analysis of patch test reactions to an Fe (II) sulfate–containing metal series in 183 consecutive patients (41 pre‐implant, 142 metal implant bearers). Test readings were on day (D)2, D3, and D6. Evaluation of questionnaire‐aided history of metal reactivity patterns and demographics of Fe reactors. Results Metal reactivity in pre‐implant/implant/total group was: to nickel 39%/30%/32%; to cobalt 17%/15%/15%; and to chromium 7%/13%/11%. Co‐sensitizations cobalt/nickel (19/58) and cobalt/chromium (11/21) were significant at P?

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