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Busulphan and thiourea as chemosterilants for the snail lymnaea acuminata

机译:Busulphan and thiourea as chemosterilants for the snail lymnaea acuminata

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AbstractTreatment of the snailLymnaea acuminatawith an alkylating agent (busulphan) or a thiocarbamide (thiourea), for 3 days, significantly reduced the number of eggs and prevented embryonic development. Both the drugs caused a dose dependent reduction in the levels of protein, DNA, RNA and the activity of the alkaline phosphatase of the ovotestis, and a dose‐dependent enhancement in the levels of amino‐acids and the activity of the acid phosphatase. Discontinuation of the drug treatment for 7 days resulted in a near complete recovery in DNA and RNA levels, while there was no change in the levels of protein, amino‐acids and the activities of the acid and alkaline phospha

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