A comprehensive evaluation of hemodynamic energy production and circuit loss using four different ECMO arterial cannulae

Silver Heinsar; Nicole Bartnikowski; Gunter HartelSamia M. FarahE‐Peng SeahEric WuSebastiano Maria ColomboClayton SemenzinAndrew HaymetIndrek R?tsepJo PaulsJohn F. FraserJacky Y. Suen

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A comprehensive evaluation of hemodynamic energy production and circuit loss using four different ECMO arterial cannulae

机译：A comprehensive evaluation of hemodynamic energy production and circuit loss using four different ECMO arterial cannulae

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Abstract Objective Pulsatile‐flow veno‐arterial extracorporeal membrane oxygenation (V‐A ECMO) has shown encouraging results for microcirculation resuscitation and left ventricle unloading in patients with refractory cardiogenic shock. We aimed to comprehensively assess different V‐A ECMO parameters and their contribution to hemodynamic energy production and transfer through the device circuit. Methods We used the i‐cor? ECMO circuit, which composed of Deltastream DP3 diagonal pump and i‐cor? console (Xenios AG), the Hilite 7000 membrane oxygenator (Xenios AG), venous and arterial tubing and a 1?L soft venous pseudo‐patient reservoir. Four different arterial cannulae (Biomedicus 15 and 17 Fr, Maquet 15 and 17 Fr) were used. For each cannula, 192 different pulsatile modes were investigated by adjusting flow rate, systole/diastole ratio, pulsatile amplitudes and frequency, yielding 784 unique conditions. A dSpace data acquisition system was used to collect flow and pressure data. Results Increasing flow rates and pulsatile amplitudes were associated with significantly higher hemodynamic energy production (both p?

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来源
《Artificial Organs》 |2023年第7期|1122-1132|共11页
作者
Silver Heinsar; Nicole Bartnikowski; Gunter HartelSamia M. FarahE‐Peng SeahEric WuSebastiano Maria ColomboClayton SemenzinAndrew HaymetIndrek R?tsepJo PaulsJohn F. FraserJacky Y. Suen;
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作者单位

Critical Care Research Group,The Prince Charles Hospital;

Statistics Unit,QIMR Berghofer Medical Research Institute;

Department of Intensive Care,North Estonia Medical CentreInnovative Cardiovascular Engineering and Technology Laboratory, Critical Care Research Group,The;

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正文语种英语
中图分类器官移植术;
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cardiogenic shock; extracorporeal membrane oxygenation; mechanical circulatory support; mock circulation loop;

A comprehensive evaluation of hemodynamic energy production and circuit loss using four different ECMO arterial cannulae

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