The evolution of the loss of life expectancy in patients with chronic myeloid leukaemia: a population‐based study in the Netherlands, 1989–2018

Carolien C. H. M. Maas; David Klaveren; Geneviève I. C. G. EctorEduardus F. M. PosthumaOtto VisserPeter E. WesterweelJeroen J. W. M. JanssenNicole M. A. BlijlevensAvinash G. Dinmohamed

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The evolution of the loss of life expectancy in patients with chronic myeloid leukaemia: a population‐based study in the Netherlands, 1989–2018

机译：The evolution of the loss of life expectancy in patients with chronic myeloid leukaemia: a population‐based study in the Netherlands, 1989–2018

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Summary Studies on the conditional life expectancy of patients with chronic myeloid leukaemia (CML) are lacking. Using data from the Netherlands Cancer Registry, we examined the life expectancy of patients with CML in the Netherlands diagnosed during 1989–2018. As of the early 2010s, the life expectancy of patients with CML who survived several years after diagnosis came narrowly close to the general population’s life expectancy, regardless of age. This finding can essentially be ascribed to the introduction and broader application of tyrosine kinase inhibitors (TKIs) and provide optimism to patients with CML who can look forward to a near‐normal life expectancy in a modern TKI era.

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来源
《British Journal of Haematology》 |2022年第5期|1219-1224|共6页
作者
Carolien C. H. M. Maas; David Klaveren; Geneviève I. C. G. EctorEduardus F. M. PosthumaOtto VisserPeter E. WesterweelJeroen J. W. M. JanssenNicole M. A. BlijlevensAvinash G. Dinmohamed;
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作者单位

Department of Public Health,Erasmus University Medical Center;

Department of Hematology,Radboudumc;

Department of Internal Medicine,Reinier de Graaf GasthuisDepartment of Registration,Netherlands Comprehensive Cancer Organisation (IKNL)Department of Internal Medicine,Albert Schweitzer HospitalAmsterdam UMC, Location VUmc, Department of Hematology,Cancer Center Amsterdam;

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正文语种英语
中图分类血液及淋巴系疾病;
关键词
chronic myeloid leukaemia; epidemiology; mathematical modelling; imatinib; leukaemia;

The evolution of the loss of life expectancy in patients with chronic myeloid leukaemia: a population‐based study in the Netherlands, 1989–2018

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