Comparison of the relation of the ESC 2021 and ESC 2013 definitions of left bundle branch block with clinical and echocardiographic outcome in cardiac resynchronization therapy

Jesse Rijks; Mohammed A. Ghossein; Philippe C. WoutersMuhammet DuralAlexander H. MaassMathias MeineMari?lle KloostermanJustin LuermansFrits W. PrinzenKevin VernooyAntonius M. W. Stipdonk

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Comparison of the relation of the ESC 2021 and ESC 2013 definitions of left bundle branch block with clinical and echocardiographic outcome in cardiac resynchronization therapy

机译：Comparison of the relation of the ESC 2021 and ESC 2013 definitions of left bundle branch block with clinical and echocardiographic outcome in cardiac resynchronization therapy

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Abstract Introduction We aimed to investigate the impact of the 2021 European Society of Cardiology (ESC) guideline changes in left bundle branch block (LBBB) definition on cardiac resynchronization therapy (CRT) patient selection and outcomes. Methods The MUG (Maastricht, Utrecht, Groningen) registry, consisting of consecutive patients implanted with a CRT device between 2001 and 2015 was studied. For this study, patients with baseline sinus rhythm and QRS duration ≥?130ms were eligible. Patients were classified according to ESC 2013 and 2021 guideline LBBB definitions and QRS duration. Endpoints were heart transplantation, LVAD implantation or mortality (HTx/LVAD/mortality) and echocardiographic response (LVESV reduction ≥15%). Results The analyses included 1.202, typical CRT patients. The ESC 2021 definition resulted in considerably less LBBB diagnoses compared to the 2013 definition (31.6% vs. 80.9%, respectively). Applying the 2013 definition resulted in significant separation of the Kaplan–Meier curves of HTx/LVAD/mortality (p?

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《Journal of cardiovascular electrophysiology》 |2023年第4期|1006-1014|共9页
作者
Jesse Rijks; Mohammed A. Ghossein; Philippe C. WoutersMuhammet DuralAlexander H. MaassMathias MeineMari?lle KloostermanJustin LuermansFrits W. PrinzenKevin VernooyAntonius M. W. Stipdonk;
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Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM),Maastricht;

Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM),Maastricht University;

Department of Cardiology,University Medical Center Utrecht (UMCU)Department of Cardiology, University Groningen,University Medical Center Groningen (UMCG);

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正文语种英语
中图分类人体生理学;
关键词
cardiac resynchronization therapy; guidelines; heart failure; left bundle branch block; patient selection;

Comparison of the relation of the ESC 2021 and ESC 2013 definitions of left bundle branch block with clinical and echocardiographic outcome in cardiac resynchronization therapy

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