Fractionated Radiotherapy After Gross Total Resection of Clival Chordoma: A Systematic Review of Survival Outcomes

Julian L. Gendreau; N. U. Farrukh Hameed; Adrian JimenezSachiv ChakravartiYusuf MehkriDebraj Mukherjee

首页> 外文期刊>Neurosurgery >Fractionated Radiotherapy After Gross Total Resection of Clival Chordoma: A Systematic Review of Survival Outcomes

【24h】

Fractionated Radiotherapy After Gross Total Resection of Clival Chordoma: A Systematic Review of Survival Outcomes

机译：Fractionated Radiotherapy After Gross Total Resection of Clival Chordoma: A Systematic Review of Survival Outcomes

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

BACKGROUND: Current treatment guidelines for clival chordomas recommend surgical resection followed by high-dose radiotherapy (RT). However, in patients in whom gross total resection (GTR) is achieved, the benefits of additional RT remain unclear. OBJECTIVE: To investigate whether RT offers any benefit to progression-free survival (PFS) in patients undergoing GTR of clival chordoma by performing a systematic review of all currently published literature. METHODS: A total of 5 databases were searched to include all studies providing data on GTR ± RT for clival chordomas (January 1990-June 2021). Qualitative assessment was performed with Newcastle-Ottawa Scale guidelines for assessing quality of nonrandomized studies. Statistical analysis using individualized patient data of PFS was performed.

著录项

来源
《Neurosurgery》 |2023年第2期|257-266|共10页
作者
Julian L. Gendreau; N. U. Farrukh Hameed; Adrian JimenezSachiv ChakravartiYusuf MehkriDebraj Mukherjee;
展开▼
作者单位

Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类头部及神经外科学;
关键词
Clival; Gross total resection. Photon; Progression-free survival; Proton; Radiotherapy; Recurrence;

Fractionated Radiotherapy After Gross Total Resection of Clival Chordoma: A Systematic Review of Survival Outcomes

摘要

著录项

相关主题

期刊订阅