Electrospun nanofibers for drug delivery applications: Methods and mechanism

Meera Moydeen Abdul Hameed; Syed Ali Padusha Mohamed Khan; Badr M. ThamerNirmala RajkumarHany El-HamsharyMohamed El-Newehy

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Electrospun nanofibers for drug delivery applications: Methods and mechanism

机译：Electrospun nanofibers for drug delivery applications: Methods and mechanism

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Electrospinning procedures such as blend electrospinning, coaxial electrospinning, and emulsion electrospinning have been used for the fabrication of electrospun nanofibers (ENFs) for biomedical applications. These ENFs are attracted great interest especially in drug delivery applications due to their small size, high surface area-to-volume, and porosity. The aim of this review is to focus on the controlled release mechanism among the different electrospinning methods, and the selectivity of hydrophilic, water-soluble polymers as a carrier for drug. The mechanism for the drug delivery depends mainly on the method of drug loading, polymeric interactions, and the nature of polymer swelling, erosion, or degradation. This review compressed on the literature survey about the fabrication of nanofibers by different electrospinning methods, factors affecting the nanofiber morphologies, selectivity of polymeric blends for successful controlled release behavior, and the mechanism involved in the drug release steps.

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来源
《Polymers for advanced technologies》 |2023年第1期|6-23|共18页
作者
Meera Moydeen Abdul Hameed; Syed Ali Padusha Mohamed Khan; Badr M. ThamerNirmala RajkumarHany El-HamsharyMohamed El-Newehy;
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作者单位

Department of Chemistry, College of Science, King Saud University;

PG and Research Department of Chemistry, Jamal Mohamed College (Affiliated to Bharathidasan University);

Department of Biotechnology, Hindustan College of Arts and Science (Affiliated to University of Madras);

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原文格式 PDF
正文语种英语
中图分类高分子化学（高聚物）;
关键词
Controlled release; Drug delivery; Electrospinning; Emulsion; Kinetics; Mechanism;

Electrospun nanofibers for drug delivery applications: Methods and mechanism

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