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Keratinocyte carcinoma as an occupational disease

机译:Keratinocyte carcinoma as an occupational disease

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摘要

Keratinocyte carcinoma (KC) comprises basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC) and are the most common forms of non-melanoma skin cancer are the most frequently diagnosed cancers among people with fair skin in Europe.1 2 People with light skin, hair or eyes are at greatest risk of KC due to their susceptibility to UV damage.3 4 Although mortality rates are relatively low, KC has high rates of morbidity and can be associated with a significant negative impact on health-related quality of life and healthcare costs.5 6 Climate change is likely to amplify this problem in the future: changes to the ozone layer will translate into higher levels of solar ultraviolet radiation (sUVR) on the earth’s surface, and therefore, the incidence of these skin cancers is expected to increase. Exposure to sUVR can take place in occupational or non-occupational settings but existing evidence indicates that occupational exposure to sUVR is an important risk factor for KC.5 sUVR is the most common occupational carcinogen in the European Union, with more than nine million workers being exposed to sUVR for at least 75% of their time at work.8 Worryingly, many outdoor workers will develop a skin cancer at some point in their lives.9 Despite this, KC is often not recognised as an occupational disease9 and there are no officially recognised European standards which aim to reduce the risk of occupational sUVR-related KC among outdoor workers.10 This has contributed to considerable heterogeneity in approaches to prevention, surveillance, diagnosis and management between and even within countries.

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