Human Fasciolosis in Iran: A Meta-analysis Study

Masoud Behzadifar; Nicola Luigi Bragazzi; Meysam BehzadifarWesam KootiIgnazio VecchioGiulia MalaguarneraMariano MartiniFarnaz Kheirandish

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Human Fasciolosis in Iran: A Meta-analysis Study

机译：Human Fasciolosis in Iran: A Meta-analysis Study

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Background: Fasciolosis, an infectious disorder with a serious public health burden, is caused by two liver flukes belonging to the genus Fasciola. Iran is among the endemic areas for this disease. This study aimed to determine the seroprevalence of human fasciolosis in Iran. Methods: A systematic search was conducted in Embase, PubMed/MEDLINE, Web of Science (WoS), and Google Scholar, as well as Iranian databases including Scientific Information Database (SID), Magiran and Irandoc from January 2000 to June 2016. In order to determine fasciolosis prevalence, the DerSimonian-Laird random model was used. In order to assess the heterogeneity among studies, I2 and Q tests were used. To investigate the source of heterogeneity, meta-regressions based on the year of publication and sample size were performed. Sensitivity analysis was carried out to ensure the stability of obtained results. Results: Eleven relevant studies were included. According to the data analysis a prevalence rate of 2% [95% CI 1-5] was found. No statistically significant relationship between gender and disease prevalence could be detected. We found an OR of developing fasciolosis of 1.67 [95% CI: 0.42 - 6.60] in people who had consumed vegetables versus those who did not eat vegetables, even though this did not yield statistical significance. Conclusion: The findings of the current study can be valuable and help the health-care workers and policy-makers in programming and implementing ad hoc interventions in order to prevent the incidence of disease.

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《Infectious disorders drug targets》 |2019年第3期|238-243|共6页
作者
Masoud Behzadifar; Nicola Luigi Bragazzi; Meysam BehzadifarWesam KootiIgnazio VecchioGiulia MalaguarneraMariano MartiniFarnaz Kheirandish;
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作者单位

Health Management and Economics Research Center, Iran University of Medical Sciences;

Department of Health Sciences (DISSAL), University of Genoa;

Department of Epidemiology, Faculty of Health and Nutrition, Lorestan University of Medical SciencesStudent Research Committee, Kurdistan University of Medical SciencesDepartment of Clinical and Experimental Medicine, University of CataniaResearch Center "The Great Senescence", University of CataniaDepartment of Health Sciences (DISSAL), Section of Ethics and History of Medicine, University ofDepartment of Parasitology and Mycology, School of Medicine, Razi Herbal Medicines Research Center;

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原文格式 PDF
正文语种英语
中图分类药学;
关键词
Human Fasciolosis; Historical evolution in Iran; systematic review; meta-analysis; seroprevalence; prevalence;

Human Fasciolosis in Iran: A Meta-analysis Study

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