Gut microbiome signatures and host colonization with multidrug-resistant bacteria

Isles N.S.; Mu A.; Kwong J.C.Howden B.P.Stinear T.P.

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Gut microbiome signatures and host colonization with multidrug-resistant bacteria

机译：Gut microbiome signatures and host colonization with multidrug-resistant bacteria

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© 2022 Elsevier LtdThe human gut is host to a diverse range of microorganisms that offer protection against colonization by multidrug-resistant bacteria. Antibiotic use, medications, health conditions, and lifestyle factors can alter the composition of the gut microbiota in such a way that results in loss of colonization resistance and increased susceptibility to invading pathogenic antibiotic-resistant bacteria. Therapeutics aiming to restore a diverse and protective microbiome are fast advancing. In this review, we focus on the compositional changes within the gut microbiome that are associated with colonization resistance and discuss their use as potential targets for therapeutics or diagnostics.

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《Trends in Microbiology》 |2022年第9期|853-865|共13页
作者
Isles N.S.; Mu A.; Kwong J.C.Howden B.P.Stinear T.P.;
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Department of Microbiology and Immunology The University of Melbourne at the Peter Doherty Institute for Infection and Immunity;

Microbiological Diagnostic Unit Public Health Laboratory The University of Melbourne at the Peter Doherty Institute for Infection and Immunity;

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正文语种英语
中图分类微生物学;
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colonization resistance; microbiome; multidrug-resistant organism (MDRO);

Gut microbiome signatures and host colonization with multidrug-resistant bacteria

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