Fasting Plasma Glucose and Glycohemoglobin with Allergic Symptoms and Specific Sensitization: Results from NHANES 2005-2006

Gan Lu; Yu-Qin Deng; Yang XiSong LiShi-Ming ChenYong-Gang KongYu XuFen LiZe-Zhang Tao

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Fasting Plasma Glucose and Glycohemoglobin with Allergic Symptoms and Specific Sensitization: Results from NHANES 2005-2006

机译：Fasting Plasma Glucose and Glycohemoglobin with Allergic Symptoms and Specific Sensitization: Results from NHANES 2005-2006

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Objective: The National Health and Nutrition Examination Survey (NHANES) data has been used to study the relationship between fasting plasma glucose (FPG) and glycohemoglobin (A1c) in patients with allergic symptoms and specific sensitization, respectively. Methods: A total of 1,687 participants and a variety of logistic regression models were selected based on the 2005-2006 NHANES (n = 10,348) for our study to describe the relationship between FPG and A1c in subjects with the sensitivity of allergic symptoms, specific sensitization and specific sensitization of 19 allergens, respectively. On this basis, a variety of logistic regression models were further established for hierarchical analysis to study the limiting conditions when FPG and A1c were related to allergic symptoms. Results: We adjusted the confounding factors and found that the risk of specific sensitization increased with the increase in FPG and A1c. Stratified analysis showed that the risk of allergic symptoms increased with the increase in FPG and A1c when born elsewhere other than in the U.S. and Mexico or underweight or overweight or with hypertension. Furthermore, we found that the risk of egg sensitization increased with the increase in FPG and A1c, while the risk of rat sensitization decreased with the increase in FPG. Conclusion: Under certain conditions, FPG and A1c were risk factors for allergic symptoms. FPG and A1c were risk factors for specific sensitization, especially egg sensitization. These findings indicate a possible link between diabetes and allergies.

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《Combinatorial chemistry & high throughput screening》 |2023年第5期|979-988|共10页
作者
Gan Lu; Yu-Qin Deng; Yang XiSong LiShi-Ming ChenYong-Gang KongYu XuFen LiZe-Zhang Tao;
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作者单位

Renmin Hospital of Wuhan University,Department of Otolaryngology, Head and Neck Surgery,,238 Jie;

Renmin Hospital of Wuhan University,Department of Otolaryngology, Head and Neck Surger,238 Jie-Fang;

Renmin Hospital of Wuhan University,Department of Otolaryngology, Head and Neck Surgery,238 JieDepartment of Otolaryngology, Head and Neck Surgery,Renmin Hospital of Wuhan University,,238 JieRenmin Hospital of Wuhan Universit,Department of Otolaryngology, Head and Neck Surgery,238 Jie-FangRenmin Hospital of Wuhan Universi,Department of Otolaryngology, Head and Neck Surgery,238 Jie-FangRenmin Hospital of Wuhan University, Wuhan,Institute of Otolaryngology-Head and Neck Surgery,,HubeiRenmin Hospital of Wuhan University,,Department of Otolaryngology, Head and Neck Surgery,,Hubei;

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正文语种英语
中图分类化学;
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Fasting plasma glucose (FPG); glycohemoglobin (A1c); allergic symptoms; specific sensitization; National Health and Nutrition Examination Survey (NHANES); specific immunoglobulin E (sIgE); diabetes.;

Fasting Plasma Glucose and Glycohemoglobin with Allergic Symptoms and Specific Sensitization: Results from NHANES 2005-2006

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