Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti-Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis

著录项

• 来源
  《Advanced Materials》 |2023年第17期|2212206.1-2212206.18|共18页
• 作者

  Fenfen Li; Ying Zhao; Zhaoxia ChengYazhou WangYale YueXiaoyu ChengJingyi SunMona Atabakhshi-KashiJundong YaoJianping DouJie YuXiuping ZhangYingqiu QiXiaotian LiXiaolong QiGuangjun Nie;

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• 作者单位

  School of Basic Medical SciencesZhengzhou UniversityZhengzhou 450001, P. R. China,M. Atabakhshi-Kashi, X. Zhang, G. NieCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,M. Atabakhshi-Kashi, X;

  M. Atabakhshi-Kashi, X. Zhang, G. NieCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,M. Atabakhshi-Kashi, X. Zhang, G. NieCenter of Materials Science and Optoelectronics EngineeringUniversi;

  M. Atabakhshi-Kashi, X. Zhang, G. NieCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijing 100049, P. R. ChinaCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijing 100049, P. R. China,Henan InstituDepartment of Interventional Ultrasound301 Hospital, 28 Fuxing Road, Beijing 100853, P. R. ChinaCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijing 100049, P. R. China,Faculty of HeSchool of Basic Medical SciencesZhengzhou UniversityZhengzhou 450001, P. R. ChinaSchool of Pharmaceutical SciencesZhengzhou University100 Kexue, Zhengzhou, Henan Province 450001, P. R. ChinaCenter of Portal HypertensionDepartment of RadiologyZhongda HospitalMedical SchoolSoutheast UniversityNanjing 210009, P. R. ChinaGBA Research Innovation Institute for NanotechnologyGuangzhou 510530, P. R. China,CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190, P. R. China,Center of Materials Science and Optoelectronics Engineering;

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• 关键词

  drug delivery; HSCs-targeted therapy; liver fibrosis; liver sinusoid barrier; LSECs fenestrae; nonalcoholic steatohepatitis;