Opioid-involved prescription drug misuse and poly-prescription drug misuse in U.S. older adults

Ty S. Schepis; Jason A. Ford; Linda WastilaSean Esteban McCabe

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Opioid-involved prescription drug misuse and poly-prescription drug misuse in U.S. older adults

机译：Opioid-involved prescription drug misuse and poly-prescription drug misuse in U.S. older adults

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Objectives: Although older adult prescription drug misuse (PDM) is associated with concerning consequences, stimulant PDM and poly- PDM involving multiple medication classes each remain understudied. Our objectives were to examine PDM and poly-PDM prevalence by medication class in US older adults and to identify the mental health, SUD, and health-related quality-of-life correlates of poly-PDM. Method: Data were from adults 50 and older completing the National Epidemiologic Survey on Alcohol and Related Conditions-III, (N = 14,667). Prevalence of PDM and poly-PDM by medication class was estimated. Logistic regression established odds of four SUD diagnoses, five psychopathology diagnoses and lifetime suicide attempts; linear regression evaluated health-related quality-of-life by PDM/poly-PDM status. Results: Past-year PDM abstinence increased with age (50-54 years: 80.5; 80 and older: 96.0), while poly-PDM declined; past-year stimulant PDM was rare (<0.6), except when combined with opioid and tranquilizer/sedative PDM. Compared to no past-year PDM, both past-year opioid-only PDM and opioid-involved poly-PDM were associated with poorer health-related quality-of-life and greater odds of psychopathology and SUD, with the highest odds in poly-PDM. Conclusion: The presence of any opioid-involved PDM in older adults highlights screening for SUD, psychopathology, and other medical conditions, with the most significant intervention needs likely in those with opioid-involved poly-PDM.

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《Aging & mental health》 |2021年第12期|2365-2373|共9页
作者
Ty S. Schepis; Jason A. Ford; Linda WastilaSean Esteban McCabe;
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Department of Psychology, Texas State University, TX, USA;

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正文语种英语
中图分类神经病学与精神病学;
关键词
Prescription drug misuse; opioid; benzodiazepine; sedative; older adult; psychopathology; substance use;

Opioid-involved prescription drug misuse and poly-prescription drug misuse in U.S. older adults

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