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首页> 外文期刊>ANZ journal of surgery. >Incidental findings on single‐photon emission computed tomography/computed tomography (SPECT/CT) lymphoscintigraphy in breast cancer: the proposed Westmead SPECT/CT incidental findings classification
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Incidental findings on single‐photon emission computed tomography/computed tomography (SPECT/CT) lymphoscintigraphy in breast cancer: the proposed Westmead SPECT/CT incidental findings classification

机译:Incidental findings on single‐photon emission computed tomography/computed tomography (SPECT/CT) lymphoscintigraphy in breast cancer: the proposed Westmead SPECT/CT incidental findings classification

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Abstract Background The aim of this study is to determine the prevalence of incidental radiological findings detected on SPECT/CT performed as part of pre‐operative lymphoscintigraphy for sentinel lymph node biopsy (SLNB) in patients undergoing breast cancer surgery and development of a modified classification to workup these lesions. Methods A retrospective audit was performed of all SPECT/CT performed in combination with lymphoscintigrams in breast cancer patients presenting with clinically node negative axillae and operated on by breast surgeons at the Westmead Breast Cancer Institute over a 12‐month period. Results Four hundred and nineteen patients were included in the study. In 149 patients (35.6), there was a total of 205 incidental findings. The most common findings were, pulmonary abnormalities (38.5), abdominal findings (27.8), thyroid nodules (14.6), cardiac abnormalities (10.7) and others (8.3). Using our proposed Westmead SPECT/CT incidental findings (WSIF) classification, 7.8 were known, 17.6 were major findings, 48.3 were minor findings, 15.1 were minimal findings and 11.2 were equivocal findings. 17.6 (n?=?36) underwent further workup and investigation and 3.4 of patients (n?=?5) required therapeutic intervention, including chemotherapy for primary lung cancer(n?=?1) and surgeries (thoracotomy, n?=?1; thyroidectomy, n?=?2; colonoscopy, n?=?1). 93.8 (n?=?393) had at least one SLN mapped, most commonly located in Level 1 of the axilla. Conclusion The incidental findings on SPECT/CT in combination with lymphoscintigraphy is within the range of previous studies (27.3–59.5). A small proportion of patients required significant major interventions (3.4). We propose that all incidental findings should be assessed according to our WSIF classification to aid in triaging need for further investigation and management.

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