Mapping PedsQL (TM) scores to CHU9D utility weights for children with chronic conditions in a multi-ethnic and deprived metropolitan population

Kelly Clare B.; Soley-Bori Marina; Lingam RaghuForman JuliaCecil LizzieNewham JamesWolfe IngridFox-Rushby Julia

首页> 外文期刊>Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation >Mapping PedsQL (TM) scores to CHU9D utility weights for children with chronic conditions in a multi-ethnic and deprived metropolitan population

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Mapping PedsQL (TM) scores to CHU9D utility weights for children with chronic conditions in a multi-ethnic and deprived metropolitan population

机译：Mapping PedsQL (TM) scores to CHU9D utility weights for children with chronic conditions in a multi-ethnic and deprived metropolitan population

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PurposeThe Child Health Utility-9 Dimensions (CHU9D) is a patient-reported outcome measure to generate Quality-Adjusted Life Years (QALYs), recommended for economic evaluations of interventions to inform funding decisions. When the CHU9D is not available, mapping algorithms offer an opportunity to convert other paediatric instruments, such as the Paediatric Quality of Life Inventory (TM) (PedsQL), onto the CHU9D scores.This study aims to validate current PedsQL to CHU9D mappings in a sample of children and young people of a wide age range (0 to 16 years of age) and with chronic conditions. New algorithms with improved predictive accuracy are also developed.MethodsData from the Children and Young People's Health Partnership (CYPHP) were used (N = 1735). Four regression models were estimated: ordinal least squared, generalized linear model, beta-binomial and censored least absolute deviations. Standard goodness of fit measures were used for validation and to assess new algorithms.ResultsWhile previous algorithms perform well, performance can be enhanced. OLS was the best estimation method for the final equations at the total, dimension and item PedsQL scores levels. The CYPHP mapping algorithms include age as an important predictor and more non-linear terms compared with previous work.ConclusionThe new CYPHP mappings are particularly relevant for samples with children and young people with chronic conditions living in deprived and urban settings. Further validation in an external sample is required.

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《Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation》 |2023年第7期|1909-1923|共15页
作者
Kelly Clare B.; Soley-Bori Marina; Lingam RaghuForman JuliaCecil LizzieNewham JamesWolfe IngridFox-Rushby Julia;
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作者单位

University of London,Inst Women & Childrens Hlth;

University of London,Kings Coll London;

Fac Hlth & Life Sci,Northumbria Univ;

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原文格式 PDF
正文语种英语
中图分类医药、卫生;
关键词
Health-related quality of life; Patient reported outcomes; Mapping algorithms; Children and young people; QUALITY-OF-LIFE; GENERIC CORE SCALES; ECONOMIC-EVALUATION; PERFORMANCE; VALIDITY; VALUES; 9D;

Mapping PedsQL (TM) scores to CHU9D utility weights for children with chronic conditions in a multi-ethnic and deprived metropolitan population

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