The Effect of the COVID-19 Lockdown on Melanoma Diagnosis in Italy

Gualdi Giulio; Porreca Annamaria; Amoruso Giuseppe FabrizioAtzori LauraCalzavara-Pinton PiergiacomoDe Tursi MicheleDi Buduo AndreaDi Marino PietroFabroncini GabriellaFantini FabrizioFargnoli Maria ConcettaGiannotta GaetanoLacarruba FrancescoLotesoriere AndreaMerli MartinaMicali GiuseppeParadisi AndreaPuviani MarioQuaglino PietroRongioletti FrancoRubatto MarcoSbano PaoloScalvenzi MassimilianoSoglia SimoneSollima LauraVillani AlessiaDi Nicola MartaAmerio Paolo

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The Effect of the COVID-19 Lockdown on Melanoma Diagnosis in Italy

机译：The Effect of the COVID-19 Lockdown on Melanoma Diagnosis in Italy

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The coronavirus disease 2019 (COVID-19) pandemic has led to lockdowns for much of the world. In Italy, all health procedures not directly related to COVID-19 were reduced or suspended, thus limiting patient access to hospitals. Any delay in cancer treatment presents the additional risk of tumors progressing from being curable to incurable. Specifically, melanoma survival rate strictly de-pends on tumor thickness, which, in turn, is a function of time. To estimate the impact on melanoma progression caused by the reduction in dermatologic services during the COVID-19 lockdown, a retro-spective observational cohort study was conducted. This study was designed to compare the clinical and histologic characteristics of the primary melanomas removed in the first 2 months after the end of the lockdown (May-July 2020) in 12 Italian centers characterized by different COVID-19 case frequencies. The control group was represented by the melanomas removed during the same period in the previous 3 years. Overall, 1,124 melanomas were considered: 237 as part of the study group and 887 from the control group (average, 295), with a 20 reduction. Breslow thickness, as well as high-risk histotypes and melanomas with vertical growth, increased for all melanomas. Ulcerated and high mitotic index melanomas increased, particularly in northern Italy. In Italy, the lockdown led to a significant worsening of melanoma severity, causing a staging jump, with a consequent worsening of outcomes. (c) 2021 Elsevier Inc. All rights reserved.

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《Clinics in dermatology》 |2021年第5期|911-919|共9页
作者
Gualdi Giulio; Porreca Annamaria; Amoruso Giuseppe FabrizioAtzori LauraCalzavara-Pinton PiergiacomoDe Tursi MicheleDi Buduo AndreaDi Marino PietroFabroncini GabriellaFantini FabrizioFargnoli Maria ConcettaGiannotta GaetanoLacarruba FrancescoLotesoriere AndreaMerli MartinaMicali GiuseppeParadisi AndreaPuviani MarioQuaglino PietroRongioletti FrancoRubatto MarcoSbano PaoloScalvenzi MassimilianoSoglia SimoneSollima LauraVillani AlessiaDi Nicola MartaAmerio Paolo;
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Dept Dermatol,Univ Turin;

Dept Publ Hlth,Univ Cagliari;

Dermatol Unit,Osped Gen BelcolleDept Clin Med & Surg,Univ Napoli Federico IIDept Dermatol,Univ BresciaPathol Unit,Osped San SalvatoreDept Med Oral & Biotechnol Sci,Univ G dAnnunzioDept Dermatol,Univ G dAnnunzioDermatol Unit,Azienda Osped CosenzaDept Med Oral Sci & Biotechnol,Univ G dAnnunzioDept Dermatol,Osped A ManzoniDept Dermatol,Univ AquilaPathol Unit,Azienda Osped CosenzaDermatol Clin,Univ CataniaDermatol Unit,Osped Gen Cristo ReDept Dermatol,Osped Sassuolo;

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正文语种英语
中图分类皮肤病学与性病学;
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SURVIVAL;

The Effect of the COVID-19 Lockdown on Melanoma Diagnosis in Italy

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