机译:Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M pro : insights into enzyme mechanism and drug design
Neutron Scattering Division, Oak Ridge National Laboratory;
Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago;
Structural Biology Center, X-ray Science Division, Argonne National LaboratoryDepartment of Biochemistry and Molecular Biology, University of Chicago;
ROOM-TEMPERATURE X-RAY CRYSTALLOGRAPHY; SARS-COV-2; 3CL MAIN PROTEASE; 3CL MPRO; CYSTEINE OXIDATION; PROTONATION STATE; ENZYME MECHANISM; DRUG DESIGN;