Stability of 28 typical prescription drugs in sewer systems and interaction with the biofilm bacterial community

Liu Anchen; Lin Wenting; Ming RuiliangGuan WenqiWang XinyingHu NingyiRen Yuan

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Stability of 28 typical prescription drugs in sewer systems and interaction with the biofilm bacterial community

机译：Stability of 28 typical prescription drugs in sewer systems and interaction with the biofilm bacterial community

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Identifying the attenuation characteristics of drugs in sewage and sewers is one of the important factors to improve the accuracy of wastewater-based epidemiology (WBE) application. In this study, 28 drugs including antidepressants, cardiovascular drugs, antihistamines, anticonvulsants and some of their human metabolites were chosen as the targets to study the hydrolysis, adsorption, and biodegradation at different temperatures in sewage and sewers. The interaction between drugs degradation and community structure of biofilm was also investigated. In the simulated sewers, the removal percentages of 12 parent or drug metabolites are 0-20, such as demethylvenlafaxine, fluvoxamine, etc., which are highly stable chemicals and suitable to be chosen as biomarkers for WBE back-calculation under appropriate circumstances. Fourteen drugs including venlafaxine and citalopram have removal percentages of 20-60. While paroxetine and sertraline, with removal percentage of 100, are the most unstable and cannot be used as biomarkers. Among the 28 drugs, there are 25 drugs that have a higher loss rate in the aerobic sewer than that in the anaerobic sewer in this study. During drug exposure in anaerobic biofilms, species abundance first decreased and then increased. Species abundance and diversity in aerobic biofilm generally showed a decreasing trend. In addition, Proteobacteria and Spirochaetota were the dominant phyla in both sewers.

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来源
《Journal of Hazardous Materials》 |2022年第1期|1-10|共10页
作者
Liu Anchen; Lin Wenting; Ming RuiliangGuan WenqiWang XinyingHu NingyiRen Yuan;
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作者单位

South China Univ Technol;

Guangzhou CAS Test Tech Serv Co Ltd;

South China Univ Technol||Minist Educ||Key Lab Environm Protect & Ecoremediat Guangdong R||South China Univ Technol;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种英语
中图分类
关键词
Attenuation characteristics; Biofilm microbial community; Biomarker; Drugs and metabolites; Wastewater-based epidemiology;

Stability of 28 typical prescription drugs in sewer systems and interaction with the biofilm bacterial community

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