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机译:Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies
Inst Biochem,Univ Innsbruck;
Ctr Med Biochem,Med Univ Vienna;
Bioinformat Inst,Agcy Sci Technol & ResDept Visceral Transplant & Thorac Surg,Med Univ Innsbruck;
precision medicine; biosensor; drug efficacy prediction; mutant BRAF; lung cancer; PROTEIN-KINASES; CANCER-THERAPY; BRAF; ACTIVATION; IMMUNOTHERAPIES; PATHWAY; CELLS; ASSAY; LIVE; MEK1;