3D printed Sr-HA/PCL scaffolds: Fabrication via liquid solvent technique

Ashtariyan Ali; Khorsand Hamid; Bavarsiha Fatemeh

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3D printed Sr-HA/PCL scaffolds: Fabrication via liquid solvent technique

机译：3D printed Sr-HA/PCL scaffolds: Fabrication via liquid solvent technique

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In this research, the Sr-HA/poly(e-caprolactone) (PCL) composite scaffold was fabricated using a solvent-based extrusion method. First, the coprecipitation method was used to synthesize the Sr-HA powders. For this purpose, strontium was doped into hydroxyapatite (HA) with molar ratios of 0, 2, 4, and 6. Then, the solvent-based extrusion method was used to manufacture the 3D printed Sr-HA/PCL scaffolds. X-ray diffraction analysis, Fourier transform infrared spectrum, and field emission scanning electron microscope of all samples calcined at 900? for 1 h indicated the formation of a single-phase HA structure. The composition of the synthesized powders was confirmed using an inductively coupled plasma test and energy-dispersive X-ray spectroscopy. The compressive strength of Sr-HA/PCL scaffolds compared with pure HA increased from 3.8 to 5.9 MPa. Results of the MTT test showed that Sr-HA/PCL scaffolds were biocompatible and the growth and proliferation of MG63 cells on the surface of scaffolds increased with the presence of strontium.

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来源
《Polymers for advanced technologies》 |2023年第7期|2355-2368|共14页
作者
Ashtariyan Ali; Khorsand Hamid; Bavarsiha Fatemeh;
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作者单位

K N Toosi Univ Technol;

Imam Khomeini Int Univ IKIU;

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原文格式 PDF
正文语种英语
中图分类高分子化合物工业（高聚物工业）;有机化学;
关键词
3D printing; composite scaffold; hydroxyapatite; liquid solvent technique; strontium; STRONTIUM-DOPED HYDROXYAPATITE; COMPOSITE; CELLS; IONS;

3D printed Sr-HA/PCL scaffolds: Fabrication via liquid solvent technique

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