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首页> 外文期刊>iranian journal of microbiology >The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children
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The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children

机译：The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children

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Background and Objectives: Infesting nearly 50 of the world's population, Helicobacter pylori are thought to cause peptic ulcers, as well as gastric adenocarcinoma. Several diagnostic methods are available to detect this bacterium; however, at least two must be used together for an accurate diagnosis. This study evaluated the use of rapid urease test for diagnosis of H. pylori infection in a pediatric population. Materials and Methods: Five gastric biopsies were taken from children during a 2-year period for the purpose of histological, molecular, bacteriological culture, and rapid urease testing. Results: Among 83 children, 38 were male, and 45 were female with an age ranging of 2 to 15 years. The infected group represented 31. The rapid urease test had a sensitivity of 88.5, a negative predictive value of 94, a specificity of 84.2, and a positive predictive value of 72. Conclusion: A rapid urease test may be appropriate for ruling out H. pylori infection after a negative result. The positive results however, may be confirmed by a second invasive test.

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