An Overview of Antiviral Properties of Bacteriophages with Emphasis on the Treatment of COVID-19 Infection

Mahsa Jalili; Nastaran Ansari; Behzad PourhosseinMaryam FazeliFarid Jalilian

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An Overview of Antiviral Properties of Bacteriophages with Emphasis on the Treatment of COVID-19 Infection

机译：An Overview of Antiviral Properties of Bacteriophages with Emphasis on the Treatment of COVID-19 Infection

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Bacteriophages or phages are the most abundant organisms in the biosphere. Scientists considered phages an appropriate tool for understanding molecular biology, horizontal gene transfer vectors, stimulants of bacterial evolution, a source of diagnostic and genetic tools, and new therapeutic agents. Therefore, studying the biology of phages and their interactions with their hosts is crucial to gaining a deeper knowledge of biological systems. Numerous studies confirmed that bacteriophages are a genetic tool with high potential for treating infectious diseases, including bacterial, fungal, and viral infections. Therefore, phages may be used as an appropriate therapeutic target against some viruses, such as COVID-19 infection. In this study, we describe the role of phages in modulating the host immune system, the production of specific antibodies against the COVID-19 virus by the host immune system, and the minimization of damage caused by the COVID-19 virus to the host. Also, the present study expresses our understanding of the prospect of phage therapy as an adjunctive therapy.

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《Infectious disorders drug targets》 |2022年第6期|22-28|共7页
作者
Mahsa Jalili; Nastaran Ansari; Behzad PourhosseinMaryam FazeliFarid Jalilian;
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作者单位

Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan;

Department of Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan,Iran;

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原文格式 PDF
正文语种英语
中图分类药学;
关键词
Bacteriophage; bacteriophage therapy; COVID-19; SARS-CoV-2; phage therapy; infectious diseases.;

An Overview of Antiviral Properties of Bacteriophages with Emphasis on the Treatment of COVID-19 Infection

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