• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >Robust fabrication of poly(lactic acid) membrane with good hemocompatibility over heparin‐mimetic graphene‐based nanosheets
【24h】

Robust fabrication of poly(lactic acid) membrane with good hemocompatibility over heparin‐mimetic graphene‐based nanosheets

机译：Robust fabrication of poly(lactic acid) membrane with good hemocompatibility over heparin‐mimetic graphene‐based nanosheets

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

Abstract Developing dislysis membranes with outstanding hemocompatibility is the key of hemodialysis used for curing the kidney malfunction. Herein, polylactic acid (PLA) membrane with high water flux (640.2 L m−2 h−1) and bovine serum albumin (BSA) rejection (>97) is prepared and subsequently modified by heparin‐mimetic sulfonated graphene oxide (SGO) via modified mussel‐inspired method. The (NH4)2Fe(SO4)2 serves as Fenton catalyst significantly accelerates the oxidized polymerization of dopamine (DA) in DA‐g‐SGO to form polydopamine‐g‐SGO (PDA‐g‐SGO). The uniform immobilization of SGO significantly improves the hydrophilicity and electronegativity of the PLA membranes, inhibiting platelets adhesion. Moreover, the sulfonic group of SGO plays the role of anticoagulant as heparin. The obtained PLA/PDA‐g‐SGO membrane exhibits excellent hemocompatibility with longer recalcification time (230 s) and lower hemolysis ratio (1.6) than those of original PLA membrane (120 s, 10.7). This study demonstrates a potential way to improve the hemocompatibility of polymeric membranes.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号