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首页> 外文期刊>Diagnostic microbiology and infectious disease >Identification of bacterial co-detections in COVID-19 critically Ill patients by BioFire (R) FilmArray (R) pneumonia panel: a systematic review and meta-analysis
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Identification of bacterial co-detections in COVID-19 critically Ill patients by BioFire (R) FilmArray (R) pneumonia panel: a systematic review and meta-analysis

机译：Identification of bacterial co-detections in COVID-19 critically Ill patients by BioFire (R) FilmArray (R) pneumonia panel: a systematic review and meta-analysis

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Among critically ill COVID-19 patients, bacterial coinfections may occur, and timely appropriate therapy may be limited with culture-based microbiology due to turnaround time and diagnostic yield challenges (e.g. antibiotic pre-exposure). We performed a systematic review and meta-analysis of the impact of BioFire (R) FilmArray (R) Pneumonia Panel in detecting bacteria and clinical management among critically ill COVID-19 patients admitted to the ICU. Seven studies with 558 patients were included. Antibiotic use before respira-tory sampling occurred in 28-79 of cases. The panel incidence of detections was 33 (95 CI 0.25 to 0.41, I-2=32) while culture yielded 18 (95 CI 0.02 to 0.45; I-2=93). The panel was associated with approximately a 1 and 2 day decrease in turnaround for identification and common resistance targets, respectively. The panel may be an important tool for clinicians to improve antimicrobial use in critically ill COVID-19 patients. (C) 2021 The Author(s). Published by Elsevier Inc.

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