Secondary Osteoporosis

Ebeling Peter R.; Nguyen Hanh H.; Aleksova JasnaVincent Amanda J.Wong PhillipMilat Frances

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Secondary Osteoporosis

机译：Secondary Osteoporosis

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Osteoporosis is a global public health problem, with fractures contributing to significant morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 of postmenopausal women, > 50 of premenopausal women, and between 50 and 80 of men have secondary osteoporosis. Exclusion of secondary causes is important, as treatment of such patients often commences by treating the underlying condition. These are varied but often neglected, ranging from endocrine to chronic inflammatory and genetic conditions. General screening is recommended for all patients with osteoporosis, with advanced investigations reserved for premenopausal women and men aged = 40 years and >= 50 years, respectively. In addition, FRAX requires adjustment in some chronic conditions, such as glucocorticoid use, type 2 diabetes, and HIV. In most conditions, evidence for antiresorptive or anabolic therapy is limited to increases in bone mass. Current osteoporosis management guidelines also neglect secondary osteoporosis and these existing evidence gaps are discussed.

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来源
《Endocrine Reviews》 |2022年第2期|240-313|共74页
作者
Ebeling Peter R.; Nguyen Hanh H.; Aleksova JasnaVincent Amanda J.Wong PhillipMilat Frances;
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作者单位

Sch Clin Sci,Monash Univ;

Dept Endocrinol,Monash Hlth;

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原文格式 PDF
正文语种英语
中图分类内分泌腺疾病及代谢病;
关键词
osteoporosis; chronic disease; fracture; secondary causes; bone mineral density; BONE-MINERAL DENSITY; CHRONIC KIDNEY-DISEASE; ADJUVANT ENDOCRINE THERAPY; INFLAMMATORY-BOWEL-DISEASE; OBSTRUCTIVE PULMONARY-DISEASE; CLINICAL-PRACTICE GUIDELINES; PEPTIDE-1 RECEPTOR AGONISTS; THYROID-STIMULATING HORMONE; PREMATURE OVARIAN FAILURE; PRIMARY BILIARY-CIRRHOSIS;

Secondary Osteoporosis

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