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Infrastructure for routine implementation of genomically enhanced applications for horse breeding in Germany

机译：Infrastructure for routine implementation of genomically enhanced applications for horse breeding in Germany

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摘要

The potential of genomics to sustainably strengthen the breeding programs of horses has been realized and implies high motivation of the equine breeding sector to implement genomically enhanced applications in routine. This means considerable challenges for the infrastructure which must be able to cope with new and increased requirements. Laboratory analyses of genome-wide markers, so-called Single Nucleotide Polymorphisms (SNPs), and related logistics play key roles in the development. For optimization of performance and reliability, the different use profiles need to be considered. Since 2017, collaborative efforts of practice and science have succeeded in increasing knowledge and providing prototypes for genomically enhanced applications. However, further steps needed to be taken before practical implementation. It was crucial to ensure that the provided closed system of digital support, starting with the order of some analysis and ending with use of the results, is in place and fully functional before the first SNP-based routine for German horse breeding was introduced in 2021. The equine genomic database allows storage and administration of SNP genotypic data generated with different platforms and chip types, such that SNP data can be efficiently used for joint analyses. Genomic services denote the new set of tools for studbooks and individual breeders that allow ordering laboratory and SNP data analyses. This area is supposed to develop dynamically to convey practical benefit of using genomic tools for horses.

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