• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >Thin‐layer photodegradable polyrotaxane gel‐immobilized surfaces for photoregulation of surface properties and cell adhesiveness
【24h】

Thin‐layer photodegradable polyrotaxane gel‐immobilized surfaces for photoregulation of surface properties and cell adhesiveness

机译：Thin‐layer photodegradable polyrotaxane gel‐immobilized surfaces for photoregulation of surface properties and cell adhesiveness

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

Abstract Thin‐layer photodegradable polyrotaxane (PRX) gel‐immobilized surfaces were fabricated to investigate the photoregulation of surface properties. Photodegradable PRXs comprising α‐cyclodextrin as a cyclic molecule, poly(ethylene glycol) as a polymer axel, and bulky trithiocarbonate as a photolabile stopper molecule (PRX‐MTP) were utilized for the fabrication of thin‐layer gels. PRX‐MTP gels were prepared on the surface of the glasses, where the surfaces were treated with an isocyanate group‐containing silane coupling agent to allow the covalent immobilization of the PRX‐MTP gels. This PRX‐MTP gel layer was disappeared upon irradiation with ultraviolet (UV; 365 nm) or visible light (465 nm) for 2 h due to the photodegradation of PRX‐MTPs. The surface wettability and roughness were changed owing to the photodegradation of the PRX‐MTP gel layer. When cells were seeded on the PRX‐MTP gel surfaces, adhesion was not observed. However, visible light irradiation of the PRX‐MTP gel layer resulted in cell adhesion on the irradiated surfaces. Consequently, it was determined that the surface properties and cell adhesiveness of the PRX‐MTP gel surfaces could be regulated by visible light irradiation. The photodegradable PRX‐MTP gel surfaces could be utilized for research on cell patterning, cell function control, and advanced cell culture system.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号