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首页> 外文期刊>ANZ journal of surgery. >The net parenchymal thickness predicts pancreatic fistula after pancreaticoduodenectomy: a retrospective cohort study of objective data
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The net parenchymal thickness predicts pancreatic fistula after pancreaticoduodenectomy: a retrospective cohort study of objective data

机译：The net parenchymal thickness predicts pancreatic fistula after pancreaticoduodenectomy: a retrospective cohort study of objective data

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Abstract Background The clinically relevant postoperative pancreatic fistula (CR‐POPF) is still a challenging complication of pancreaticoduodenectomy (PD). This study aims to explore the predictors of CR‐POPF after PD, including net parenchymal thickness (NPT) of pancreatic neck. Methods The consecutive patients who underwent PD at a tertiary hospital were retrospectively reviewed. Univariate and multivariate analyses were conducted on the perioperative data, which was mainly extracted from the objective data, containing the results from the laboratory tests and the imaging examination. NPT refers to the total thickness of pancreatic gland excluding main pancreatic duct (MPD) at the CT film. Results Univariate analyses showed that total serum bilirubin (TBiL) and albumin (ALB) levels, MPD size and NPT were significantly different between the patients with and without CR‐POPF. The white blood cell count, the rate of intra‐abdominal infection (IAI) and the postoperative length of hospital stay (LOS) were associated with the incidence of CR‐POPF. The proportion of patients with pancreatic adenocarcinoma or chronic pancreatitis was significantly lower in the CR‐POPF group than in the non‐CR‐POPF group. Multivariate analyses manifested that ALB ≤35?g/L and NPT >10?mm were two of the independent risk factors for CR‐POPF. Conclusion Preoperative ALB ≤35?g/L and NPT >?10?mm were both the independent predictors of CR‐POPF. CR‐POPF was associated with the higher IAI rate and the extended LOS.

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