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Antibiotic use, gastroenteritis and respiratory illness in South Australian children.

机译:Antibiotic use, gastroenteritis and respiratory illness in South Australian children.

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摘要

This study examines the incidence of antibiotic-associated diarrhoea (AAD) in children in the community setting. Parents of 965 children aged 4-6 years and resident in rural/semi-rural South Australia completed a questionnaire on socio-demographic factors, and a 6-week daily diary detailing symptoms of gastroenteritis, antibiotic use, respiratory illness, and contact with someone with gastroenteritis. The incidence of AAD was 32.3 , falling to 23.5 when episodes associated with a respiratory illness were excluded. Respiratory illness in the previous 3 days (OR 6.76, 95 CI 4.87, 9.38), and contact with someone with gastroenteritis in the previous 14 days (OR 1.8, 95 CI 1.48, 2.19), were both associated with gastroenteritis. After adjusting for these, only the first day of antibiotic use was associated with gastroenteritis (OR 3.8, 95 CI 1.8, 8.06). Potential confounding factors, in particular inter-current respiratory illness, need to be considered when examining AAD.

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