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>Skin tests with tuberculin (PPD)Candida albicansand Trichophyton spp. in cryptogenic fibrosing alveolitis and asbestos related lung disease
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Skin tests with tuberculin (PPD)Candida albicansand Trichophyton spp. in cryptogenic fibrosing alveolitis and asbestos related lung disease
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机译:Skin tests with tuberculin (PPD)Candida albicansand Trichophyton spp. in cryptogenic fibrosing alveolitis and asbestos related lung disease
SummaryDelayed skin hypersensitivity responses were elicited in patients with cryptogenic fibrosing alveolitis (CFA) (twenty‐eight), asbestosis (eight), mesothelioma (eight) and a ‘control’ group, having miscellaneous lung diseases not normally believed to be associated with T cell deficiency (twenty). Three antigens,Candida albicans, trichophyton and purified protein derivative (PPD) in a range of doses were used.There was no evidence of impaired cellular immunity in CFA or in mesothelioma, indeed there was a significantly increased frequency of reactions to PPD in both of these conditions (P<0.05 andP<0.01 respectively). There was, however, a trend of decreased responsiveness in the group with asbestosis.The dosage regimen used rarely gave completely negative results (only one of thirty‐two completed tests), and may provide a basis for a simple and standard regimen for screening patients suspected of having defective T cell re
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