Excessive uterine bleeding is one of the most common complaints encountered in the perimenopausal years. The broad spectrum of etiologies includes both genital and extragenital causes. Dysfunctional uterine bleeding (DUB) is defined as abnormal uterine bleeding with no demonstrable organic cause, genital or extragenital, and occurs most often at extremes of the reproductive years, a time when anovulation is common. It is a diagnosis of exclusion, which can be made only after all other causes have been ruled out. Approximately half of the women with DUB are 40 to 50 years of age.
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